The α-chain consists of four or five extracellular domains: a seven-bladed β-propeller, a thigh, and two calf domains. Nine of the 18 integrin α chains have an ...
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Jun 29, 2021 · Recognition of laminin by integrin receptors is central to the epithelial cell adhesion to basement membrane, but the structural background ...
Jan 2, 2023 · The common structure of different α-subunits present in their extracellular domain are seven repeat motifs, which fold into a seven-bladed ...
Oct 7, 2020 · Integrins are heterodimeric transmembrane cell adhesion molecules made up of alpha (α) and beta (β) subunits arranged in numerous dimeric ...
In their roles as major adhesion receptors, integrins signal across the plasma membrane in both directions. Recent structural and cell biological data ...
Jun 1, 2007 · (b) The I (inserted or interactive) domain is present in seven human α subunits between β-propeller repeats 2 and 3, and is involved in ligand ...
The vitronectin receptor mediates cell adhesion to the extracellular matrix proteins vitronectin ... Integrin RGD Binding Domain 2171 FIG. 3. The ... T. A.. Lam ...
This superfamily represents a region containing the β-propeller folds found at the N terminus of integrin alpha. Integrins are the major metazoan receptors for ...
The N-terminal ≈440 aa of integrin α subunits contain seven sequence repeats. These are predicted here to fold into a β-propeller domain.
Consensus sequence repeats define the seven blades of the integrin alpha N-terminal domain · Defining a structure-based motif for blades of the human-type β- ...